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Thomas, Sean


Department of Microbiology & Molecular Genetics
567 Wilson Road Room 5100
Michigan State University
East Lansing, MI 48824
(517) 884-5329




Sean Thomas is a second-year PhD student in the Microbiology and Molecular Genetics department in Dr. Andrew Olive’s laboratory. Here, he studies interactions between the host innate immune system and the chronic intracellular pathogen Mycobacterium tuberculosis to identify potential host-directed therapeutics that effectively augment the ability of the host immune system to control the onset of active tuberculosis. Currently, he is working on identifying interactions between NADPH Phagocyte Oxidase and Caspase-1 that result in severely worsened Mtb disease progression in mice deficient in both complexes, but not either separately. He graduated from Southeast Missouri State University in 2017 with a B.S. in Biochemistry and Molecular Biology with a minor in Physics, where he previously researched fungal growth kinetics and manipulated magnetic nanoparticle properties to create toxic microenvironments within the bloodstream.