Department of Microbiology & Molecular Genetics
5156 Biomedical Physical Sciences
Michigan State University
East Lansing, MI 48824
Beth Ottosen is a second year Ph.D. student in the department of Microbiology and Molecular Genetics. Her research interests center around better understanding the pathogenesis of multidrug-resistant opportunistic infections and identifying novel targets for therapeutic intervention in these difficult to treat organisms. To date, she has studied three of the six ESKAPE pathogens designated as serious antibiotic resistant threats in hospital settings. In the DiRita lab, Beth studies genetic factors contributing to Enterobacter cloacae infection and colonization of the gastrointestinal tract. Beth received her B.S. in Microbiology from the University of Michigan, where she studied genes important for cell envelope integrity in multidrug-resistant Acinetobacter baumannii. Outside of the lab, she is active in the MMG Graduate Student Workshop, and is a member of the Graduate Women in Science organization.
- Crepin S, Ottosen EN, Sintsova A, Ernst RK, Mobley HLT (2019). The UDP-GalNAcA sugar biosynthesis genes gna-gne2 are required to maintain cell envelope integrity and in vivo fitness in multi-drug resistant Acinetobacter baumannii. Molecular Microbiology.
- Crepin S, Ottosen EN, Peters K, Smith SN, Himpsl SD, Vollmer W, Mobley HLT (2018). The lytic murein transglycosylase MltB connects membrane homeostasis and in vivo fitness of Acinetobacter baumannii. Molecular Microbiology. 109(6):745-762
- Ottosen EN, Hesse L, Brown B, Francis R, Choby J, Surdel M, Skaar EP, Hammer ND. (2019). IspA and wall teichoic acid promote metabolic versatility in Staphylococcus aureus. Poster presentation at Midwest Microbial Pathogenesis Conference, Toledo, OH.