Dazzo, Frank B.
B.S. 1970, Florida State University
M.S., 1972, University of Florida
Ph.D., 1975, University of Florida
NSF Postdoctoral Fellow, 1976-1977, University of Wisconsin
Department of Microbiology and Molecular Genetics
6174 Biomedical Physical Sciences
Michigan State University
East Lansing, MI 48824
Phone: (517) 884-5394
I conduct basic and applied research on beneficial plant-bacteria associations of agricultural importance, especially those involving the nitrogen-fixing bacterium, Rhizobium. A main focus has been on elucidating the events leading to successful infection of clover roots by the Rhizobium leguminosarum bv. trifolii microsymbiont, and the subsequent development of nitrogen-fixing root nodules. We also investigate a newly described natural association between Rhizobium and cereals (e.g., rice and wheat), and are exploring ways to increase cereal production under real-world agronomic conditions by exploiting the benefits of this plant-microbe association. A second research focus is the development of CMEIAS, a new generation of interactive computer software that combines the resolving power of microscopy with digital image analysis to strengthen microscopy-based approaches for understanding microbial ecology in situ at single cell resolution. Various natural and managed communities and a wide range of digital microscopies are being used for that work.
Yanni, RY Rizk, FK Abd El-Fattah, A Squartini, V Corich, A Giacomini, F deBruijn, J Rademaker, J Maya-Flores, P Ostrom, M Vega-Hernandez, RI Hollingsworth, E. Martinez-Molina, P Mateos, E Velazquez, J Wopereis, E Triplett, M Umali-Garcia, JA, Anarna, BG Rolfe, JK Ladha, J Hill, R Mujoo, PK Ng, and F.B. Dazzo. 2001. The beneficial plant growth-promoting endophytic association of Rhizobium leguminosarum bv. trifolii with rice roots. Austr. J. Plant Physiol., 28: 845-870.
Chi, F., Shi-Hua Shen, Hai-Ping Cheng, Yu-Xiang Jing, Youssef G. Yanni, and F. B. Dazzo. 2005. Ascending migration of endophytic rhizobia from roots to leaves inside rice plants and assessment of their benefits to the growth physiology of rice. Appl. Environ. Microbiol. 71: 7271-7278. DOI: 10.1128
Robledo, M., J. I. Jiménez-Zurdo, E. Velázquez, M.E. Trujillo, J. L. Zurdo-Piñeiro, M. H. Ramírez-Bahena, B. Ramos, J. M. Díaz-Mínguez, F. Dazzo, E. Martínez-Molina and P. F. Mateos. 2008. Rhizobium cellulase CelC2 is essential for primary symbiotic infection of legume host roots. Proc. National Academy of Sciences, USA, 105:7064-7069.
F. B. Dazzo. 2012. CMEIAS-aided microscopy of the spatial ecology of individual bacterial interactions involving cell-to-cell communication within biofilms. Sensors 12: 7047-7062 DOI: 10.3390/s120607047
Dazzo, F.B., K. Klemmer, R. Chandler and Y. G. Yanni. 2013. In situ ecophysiology of microbial biofilm communities analysed by CMEIAS computer-assisted microscopy at single-cell resolution. Diversity 5: 426-460. DOI:10.3390/d5030426
Folland, I., D. Trione and F. B. Dazzo. 2014. Accuracy of biovolume formulas for CMEIAS computer-assisted microscopy and body size analysis of morphologically diverse microbial populations and communities. Microbial Ecology 68: 596-610.
Dazzo, F.B., and B.C. Niccum. 2015. Use of CMEIAS image analysis software to accurately compute attributes of cell size, morphology, spatial aggregation and color segmentation that signify in situ ecophydiological adaptations in microbial biofilm communities. Computation: 3:72-98.
Dazzo, Frank B., R. Sexton, A. Jain, A. Makhoul, M. Shears, D. Gusfa, S. Handelsman, B. Niccum and D. Onsay. 2017. Influence of substratum hydrophobicity on the geomicrobiology of river biofilm architecture and ecology analyzed by CMEIAS bioimage informatics. Geosciences 7, 56. 35 pages. DOI: 10.3390/geosciences7030056
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